Discussione: Folding@Home
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Old 19-12-2008, 20:03   #1004
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Iscritto dal: Sep 2006
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Noto or ora che non ho messo in prima pagina codesto link


Ovvero dove lo staff pubblica tutte le news legate al progetto

Ora, come potete vedere hanno parecchie pubblicazioni scientifiche (che non è l'articoletto su La Stampa eh....) in corso di approvazione e pubblicazione! Ciò è un GRAN risultato, già una pubblicazione da sola può essere MOLTO importante, qua ne hanno svariate quindi...

Ma in particolare vorrei porre l'attenzione sull'ultima news

New FAH results on possible new Alzheimer's drug presented

This is very preliminary news, but something I'm very, very excited about, so I'll give some advance news. On Tuesday, we presented our results regarding new possible drugs (small molecule leads) to fight Alzheimer's Disease at a recent meeting at Stanford. This meeting was part of the NIH Roadmap Nanomedicine center (http://proteinfoldingcenter.org/) retreat and was supported by NIH grants to Folding@home.
It's very early (so we are not publicly talking about the details until this has passed peer review), but we are very excited that it looks like we may have multiple small molecules which appear to inhibit toxicity of Abeta, the protein which is the toxic element in Alzheimer's Disease.

This is exciting in many ways. It's been a long road for FAH to get to this point, but we are starting to see the possibility of seeing these results published easily before our 10th birthday (October 2010). Considering all the technology development that had to be done in the first five years, these results have come very quickly (in the last 3 years), which is exciting. In particular, we are now looking to apply these methods to other protein misfolding diseases (we have pilot projects for Huntington's Disease underway).

Finally, I should stress that while we're very excited about this, it's still early and a lot can go wrong between where we are and having a drug that doctors can prescribe. Over the holidays, we will be double checking the experimental data, crossing t's and dotting i's to make sure there is nothing missed before we think about submitting this for peer reviewed publication. Also, there is still a long way from an interesting possible drug (where we are now) to something which has passed FDA clinical trials (where we'd love to be), and a lot can go wrong in clinical trials in particular.

Thus, this is an important milestone for FAH and we are very grateful to all who have contributed. Happy holidays to all!
Materiale parecchio promettente per curare l'alzheimer

Dedicato a tutti quelli che "ma si ma tanto è il seti, alieni, bla bla, spreco di tempo, non ci sono risultati bla bla e l'ambiente e l'anidride carbonica!" che si meriterebbero calci nel didietro ma non lo diciamo se no mi bannano (però mi sa che mi bannano lo stesso, porca miseria...vabbè!)

Ah, e aggiornate al client 6.23, susu!
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